What is the hydrocortisone dose equivalent to 25 mg of cortisone?

What is the hydrocortisone dose equivalent to 25 mg of cortisone?

• A. 25 mg
• B. 20 mg
• C. 30 mg
• D. 15 mg

Answer: (B)

Glucocorticoid dose equivalence means different steroids require different milligram amounts to achieve the same anti-inflammatory effect. Cortisone acetate is converted in the body to its active form, hydrocortisone, and the potency per milligram is slightly lower than hydrocortisone. In practice, 25 mg of cortisone acetate is roughly equivalent to 20 mg of hydrocortisone. So to replace 25 mg of cortisone with hydrocortisone, you would give about 20 mg. The other options would be too high or too low to match the same effect.

Glucocorticoid dose equivalence means different steroids require different milligram amounts to achieve the same anti-inflammatory effect. Cortisone acetate is converted in the body to its active form, hydrocortisone, and the potency per milligram is slightly lower than hydrocortisone. In practice, 25 mg of cortisone acetate is roughly equivalent to 20 mg of hydrocortisone. So to replace 25 mg of cortisone with hydrocortisone, you would give about 20 mg. The other options would be too high or too low to match the same effect.