How should methotrexate be stored?

How should methotrexate be stored?

• A. At room temperature
• B. Refrigerated at 4°C
• C. Frozen
• D. In the freezer

Answer: (A)

Stability of the oral methotrexate tablet is best maintained at room temperature. Keep it around 20-25°C (with any manufacturer-specified allowable range), in its original container, tightly closed, and protected from light and moisture. Refrigeration or freezing isn’t required for this form and can risk stability or dosing accuracy, so room-temperature storage is the standard recommendation. If you’re using a different formulation (like an injectable), always follow the label for that specific product.

Stability of the oral methotrexate tablet is best maintained at room temperature. Keep it around 20-25°C (with any manufacturer-specified allowable range), in its original container, tightly closed, and protected from light and moisture. Refrigeration or freezing isn’t required for this form and can risk stability or dosing accuracy, so room-temperature storage is the standard recommendation. If you’re using a different formulation (like an injectable), always follow the label for that specific product.