Certolizumab, sold under Cimzia, has which subcutaneous dose?

Certolizumab, sold under Cimzia, has which subcutaneous dose?

• A. Cimzia 200 mg SQ
• B. Cimzia 400 mg SQ
• C. Cimzia 50 mg SQ
• D. Cimzia 400 mg IV

Answer: (B)

Certolizumab pegol is given by subcutaneous injection, and the amount delivered per dose is 400 mg. In practice, patients start with a loading schedule of 400 mg at weeks 0, 2, and 4, then continue with 400 mg every 2 weeks for many indications, or every 4 weeks for Crohn’s disease depending on the regimen. The other options don’t fit because Cimzia isn’t dosed at 200 mg or 50 mg per injection, and it is administered subcutaneously rather than intravenously.

Certolizumab pegol is given by subcutaneous injection, and the amount delivered per dose is 400 mg. In practice, patients start with a loading schedule of 400 mg at weeks 0, 2, and 4, then continue with 400 mg every 2 weeks for many indications, or every 4 weeks for Crohn’s disease depending on the regimen. The other options don’t fit because Cimzia isn’t dosed at 200 mg or 50 mg per injection, and it is administered subcutaneously rather than intravenously.