A notable adverse effect of Sulfasalazine is which of the following?

A notable adverse effect of Sulfasalazine is which of the following?

• A. Discoloration of bodily fluids (Yellow/orange)
• B. Hyperkalemia
• C. Hyperglycemia
• D. Bradycardia

Answer: (A)

Sulfasalazine often causes orange-yellow discoloration of urine and other bodily fluids. This cosmetic effect comes from the drug’s metabolism and excretion, particularly the sulfapyridine fragment that can tint excretions as it’s eliminated. It’s a harmless, expected reaction and doesn’t indicate toxicity. Hyperkalemia, hyperglycemia, and bradycardia are not typical effects of sulfasalazine; they aren’t related to its common adverse profile and would suggest other causes or medications.

Sulfasalazine often causes orange-yellow discoloration of urine and other bodily fluids. This cosmetic effect comes from the drug’s metabolism and excretion, particularly the sulfapyridine fragment that can tint excretions as it’s eliminated. It’s a harmless, expected reaction and doesn’t indicate toxicity.

Hyperkalemia, hyperglycemia, and bradycardia are not typical effects of sulfasalazine; they aren’t related to its common adverse profile and would suggest other causes or medications.